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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36933 | Cdk2 Inhibitor II | Cdk2 Inhibitor II,CDK2-IN-3 | CDK |
Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM. | |||
T6866 | AUZ 454 | K03861 | CDK |
AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. | |||
T3935 | 1-Naphthyl PP1 | 1-NA-PP 1 | Src |
1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively) | |||
T3186 | NU2058 | O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine | Topoisomerase , CDK |
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity. | |||
T7371 | 1-Naphthyl PP1 hydrochloride | 1-NA-PP 1 hydrochloride | Src |
1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src | |||
T14919 | CDKI-73 | Apoptosis , CDK | |
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effe... | |||
T76377 | Cdk2/Cyclin Inhibitory Peptide II | ||
Cdk2/Cyclin Inhibitory Peptide II (Tat-LDL), a CDK2 inhibitor, demonstrates dose-dependent cytotoxic effects on U2OS osteosarcoma cells [1]. | |||
T62337 | CDK2-IN-11 | ||
CDK2-IN-11 (compound 9d) is a potent inhibitor of CDK2 (IC50: 6.4 μM) and acts on hCA II (Ki: 23.4 nM), hCA IX (Ki: 56.3 nM) and hCA XII (Ki: 44.3 nM). CDK2-IN-11 can be used in anticancer studies. | |||
T62668 | CDK2-IN-12 | ||
CDK2-IN-12 (compound 10b) is a potent inhibitor of CDK2 (IC50: 11.6 μM). CDK2-IN-12 exhibits inhibition of hCA subtypes I, II, IX and XII with KI values of 3534, 638.4, 44.3 and 48.8 nM, respectively. CDK2-IN-12 shows CD... | |||
T61842 | Carbonic anhydrase inhibitor 14 | ||
Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibit... | |||
T63070 | EGFR-IN-45 | ||
EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR), acting on EGFR (IC50: 0.4 μM) and CDK2 (IC50: 1.6 μM). EGFR-IN-45 also inhibits the topoisomerases Topo I and Topo II. EGFR-IN-45 block... | |||
T62235 | CDK-IN-9 | ||
CDK-IN-9 (compound 24) is a potent inhibitor of CDK. CDK-IN-9 is also a molecular gel that induces interaction between CDK12 and DDB1 and is able to act on CDK2/E (IC50: 4 nM). CDK-IN-9 can be used to dephosphorylate ret... | |||
T73633 | YKL-5-124 TFA | ||
YKL-5-124 TFA, a potent and selective irreversible covalent inhibitor of CDK7, demonstrates IC50 values of 53.5 nM for CDK7 and 9.7 nM for the CDK7/Mat1/CycH complex. It exhibits over 100-fold selectivity for CDK7 over C... |